Abstract
Background. This study describes antimicrobial, anticancer and antioxidant properties of Sauropus androgynus stem extract. The main objective of the present study was to reveal the potential of S. androgynus strip to be used as a medicinal drug.
Materials and methods. The antimicrobial properties of S. androgynus stem extract against Aeromonas hydrophila, Escherichia coli, Edwardsiella tarda, Flavobacterium sp., Klebsiella sp., Salmonella sp., Vibrio alginolyticus, V. parahaemolyticus, V. cholerae and Pseudomonas aeruginosa were revealed by using the broth micro-dilution method, whereas the anticancer effects of the extract was determined with a colorimetric MTT (tetrazolium) assay against human breast adenocarcinoma (MCF-7). The antioxidant activity of the plant extract was characterized also by using a α, α-diphenyl-β-picrylhydrazyl (DPPH) radical scavenging method. Finally, chemical compounds of the plant extract were screened and identified by using gas chromatography – mass spectrometry (GC–MS).
Results. The minimum inhibitory concentration (MIC) values ranged from 7.81 to 62.5 mg/l in which the plant extract was found to inhibit the growth of Edwardsiella tarda, Escherichia coli, Flavobacterium sp., Pseudomonas aeruginosa and Vibrio cholerae at 7.81 mg/l, Klebsiella sp., Aeromonas hydrophila and Vibrio alginolyticus at 15.6 mg/l, and it was able to control the growth of Salmonella sp. and Vibrio parahaemolyticus at 62.5 mg/l. The results of the present study has shown S. androgynus stem extract to possess a high antimicrobial activity and a moderate antioxidant activity (inhibition concentration 50%; IC50 of DPPH is 8 ppt), but no anticancer activity. A total of 34 compounds were identified in the plant extract in which the major compounds were 9, 12, 15-octadecatrienoic acid, methyl ester, (Z, Z, Z)- (14.48%) and phytol (13.08%).
Conclusions. S. androgynus stem extract can be used as an antimicrobial and antioxidant agents.
Keywords: antimicrobial, antioxidant, anticancer, chemical compound, Sauropus androgynus stem
Downloads
Download data is not yet available.
Most read articles by the same author(s)
-
Sandra Strainienė,
Kipras Jauniškis,
Ilona Savlan,
Justinas Pamedys,
Ieva Stundienė,
Valentina Liakina,
Jonas Valantinas,
Paraneoplastic Phenomena of Disseminated Intravascular Coagulopathy in Hepatic Angiosarcoma – Rare, Challenging and Fatal. Case Report and Literature Review
,
Acta medica Lituanica: Vol. 28 No. 2 (2021): Acta medica Lituanica
-
Monika Kapitančukė,
Agnija Vaščiūnaitė,
Rasa Augustinienė,
Jūratė Sakalinskienė,
Gražina Kleinotienė,
Primary gastric Burkitt lymphoma-induced anaemia: a case report and a literature review
,
Acta medica Lituanica: Vol. 25 No. 1 (2018)
-
Eleonora Ivanova,
Beata Vincel,
Gilvydas Verkauskas,
Faruk Hadziselimovic,
Gubernaculum and Epididymo-Testicular Descent: Review of the Literature
,
Acta medica Lituanica: Vol. 29 No. 2 (2022): Acta medica Lituanica
-
Evelina Kodzis,
Donatas Jocius,
Ona Lapteva,
Rugilė Kručaitė ,
Common Options and Overlooked Alternative for Drainage of Inaccessible Presacral Abscess: A Case Report
,
Acta medica Lituanica: Vol. 28 No. 1 (2021): Acta medica Lituanica
-
Roberts Rumba,
Sandra Cipkina,
Fanija Cukure,
Andrejs Vanags,
Systemic and local inflammation in colorectal cancer
,
Acta medica Lituanica: Vol. 25 No. 4 (2018)
-
Mindaugas Gailiušas,
Judita Andrejaitienė,
Edmundas Širvinskas,
Darijus Krasauskas,
Milda Švagždienė,
Birutė Kumpaitienė,
Association between serum biomarkers and postoperative delirium after cardiac surgery
,
Acta medica Lituanica: Vol. 26 No. 1 (2019): Acta Medica Lituanica
-
Ieva Norkienė,
Raquel d’Espiney,
Juan F. Martin-Lazaro,
Effectiveness of high-flow nasal oxygen therapy in management of acute hypoxemic and hypercapnic respiratory failure
,
Acta medica Lituanica: Vol. 26 No. 1 (2019): Acta Medica Lituanica
-
Mehdi Maghbooli,
Abdolreza Esmaeilzadeh ,
Fatemeh Karami Zarandi,
Arezoo Jafarzadeh ,
Sajjad Biglari ,
Nazanin Azizi Shalbaf ,
Negar Farhoudi ,
Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?
,
Acta medica Lituanica: Vol. 28 No. 2 (2021): Acta medica Lituanica
-
Aurelija Kemežytė,
Dario Piombino-Mascali,
Bioarchaeological Notes on the Commingled Human Remains Held in the Church of Saint Francis of Paola, Sant’Angelo di Brolo, Sicily, Italy
,
Acta medica Lituanica: Vol. 29 No. 1 (2022): Acta medica Lituanica
-
Emrah Doğan,
Sabri Serhan Olcay,
Tuba Çınar Olcay,
Utku Tapan,
Ozge Oral Tapan,
Fatih Alaşan,
A case of post-COVID-19 fibrosis mimicking Thoracic Manifestation of Ankylosing Spondylitis.
,
Acta medica Lituanica: Vol. 29 No. 1 (2022): Acta medica Lituanica